Sodium valproate and routine liver function tests.
نویسنده
چکیده
منابع مشابه
Non-Hyperammonemic valproate encephalopathy
A 21-year-old male known case of primary hypothyroidism, Seizure disorder sequelae of an old trauma receiving sodium valproate, clobazam and phenobarbitone for control of Generalized tonic clonic seizures reported to neurology OPD with history of altered sensorium and gait unsteadiness for 1 week with history of hike in valproate dose 2 weeks before. On examination he was drowsy. Neurological e...
متن کاملA Case of Valproate Induced Hyperammonemic Encephalopathy
A 36-years-old man on phenytoin, levetiracetam, and sodium valproate presented with acute confusion. Routine investigations including serum valproate and phenytoin concentration were normal. His serum ammonia concentration was raised. His valproate was held and 2 days later he recovered with concordant normalisation of serum ammonia concentration. Urea acid cycle disorder was ruled out, and a d...
متن کاملEvaluation of Liver Enzymes Rising in Patients Treated with Sodium Valproate (VPA)
Introduction Valproic acid (VPA, Valproate) is an eight-branch fatty acid and varies from other antiepileptic drugs. VPA use might lead to mild to severe hepatotoxicity. The aim of this study was to investigate valproic acid impact on liver transaminases at the beginning of VPA treatment and after three and six months of it. Materials and Methods This study was designed as a cross sectional pro...
متن کاملمقایسه اثر داروی سدیم والپروات و کاربامازپین بر عملکرد جنسی در بیماران مصروع مذکر شهر همدان
Background & Objective: Although antiepileptic drugs have controlled the epilepsy attacks substantially, the side-effects are still considered as a problem to the patients. The aim of this study was to compare the effects of sodium valproate and carbamazepine on sexual function in men with epilepsy. Materials & Methods: In this cross-sectional study 35 male married epileptic patients with the ...
متن کاملAcute liver impairment after sodium valproate overdose.
Liver impairment is a recognised adverse effect of long-term sodium valproate treatment, but there are few reports concerning its occurrence after acute overdose. This report describes a 36-year-old woman who deliberately ingested 32 g of sodium valproate (Epilim). Serum valproate concentration was 4370 μmol/l (630 mg/l) at 4.3 h post-ingestion (therapeutic reference range: 300-600 μmol/l), and...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 59 9 شماره
صفحات -
تاریخ انتشار 1984